Recrystallization and Acid/Base Extraction
Salt The product from the reaction of an acid and a base Freebase The natural form of a drug, hasn't been reacted with an acid. You can change it back and forth between its freebase and salt form as many times as you want. Explanation of A/B (acid base) extraction. Most drugs have an amine group. This is a NH 2 attached to the molecule somewhere.